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Cat. No.: HY-162833

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Antileishmanial agent-30

Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC₅₀, CC₅₀, and SI of 0.2 μM, >100 μM and >500 for L. donovani.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₁N₅O₂
Molecular Weight:399.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Antileishmanial agent-30 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC₅₀, CC₅₀, and SI of 0.2 μM, >100 μM and >500 for L. donovani^[1].

All Parasite Isoforms :

Chemical Information

Molecular Weight 399.45
Formula C₂₃H₂₁N₅O₂
SMILES

O=C(NNC(CC1=NC2=CC=CC=C2N1C)=O)C3=NC=C(C4=CC=C(C)C=C4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bernhard Jandl, et al. Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega. 2024 Aug 22;9(35):37170-37182. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Antileishmanial agent-30

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Antileishmanial agent-30 Related Classifications

HY-162833 Related Classifications