Antitumor agent-213
Antitumor agent-213 is an antitumor agent. Antitumor agent-213 binds to epidermal growth factor receptor (EGFR) and shows antitumor activity. Antitumor agent-213 can inhibit cancer cells proliferation, migration and induces apoptosis. Antitumor agent-213 can be used for the research of cancer, such as liver cancer.
For research use only. We do not sell to patients.
- Formula: C25H24ClN5O5
- Molecular Weight:509.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Apoptosis inducer 58 (Compound 5d) inhibits HepG2 and THLE-2 cell growth with IC50 of 4.82 and 16.2 μM[1].
Antitumor agent-213 (5-15 μM; 72 h) induces apoptosis and inhibits migration in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 509.94
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Formula C25H24ClN5O5
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SMILES
O=C(NNC1=C2C(C(OCC)=O)=C(OC2=NC(NC3=CC=C(C=C3)Cl)=N1)C)COC4=CC=CC=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)