AR-12463
AR-12463 is a derivative of Trapidil (HY-B1016). AR-12463 inhibits the conversion of [14C]acetate to cholesterol. AR-12463 significantly reduces the elevation of total cholesterol in rabbit serum and prevents cholesterol incorporation into tissues. AR-12463 can be used to study atherosclerosis.
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- CAS. Nr.: 100557-04-8
- Formel: C17H28N6O
- Molecular Weight:332.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 100557-04-8
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Molecular Weight 332.44
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Formel C17H28N6O
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SMILES
OCCN(CCCCC)C1=CC(N2CCCCC2)=NC3=NC=NN31
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50(1):101-7. PMID: 1859385. [Content Brief]
[2]. Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50(1):101-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AR-12463 Related Classifications
HY-113526 Related Classifications
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