BMS 561390
BMS 561390 (DPC 083) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 214287-99-7
- Formel: C14H12ClF3N2O
- Molecular Weight:316.71
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
|
HIV-1 (WT) 2.0 nM (IC50) |
HIV-1 (K103N) 21 nM (IC50) |
HIV-1 (L100I) 5.9 nM (IC50) |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 214287-99-7
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Molecular Weight 316.71
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Formel C14H12ClF3N2O
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SMILES
O=C1NC2=C(C=C(Cl)C=C2)[C@](C(F)(F)F)(/C=C/C3CC3)N1
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Synonyms
DPC 083
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)