BMS-978299
BMS-978299 is an IRAK4 inhibitor that can be used for the study of immune disorders.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1610016-88-0
- Formel: C21H24FN5O2S
- Molecular Weight:429.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
IRAK4 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
230 nM
Compound: 12
|
Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
|
[PMID: 32676146] |
Chemical Information
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CAS. Nr. 1610016-88-0
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Molecular Weight 429.51
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Formel C21H24FN5O2S
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SMILES
C(NC[C@H](C(C)(C)O)F)(=O)C=1C(NC2CC2)=CC(NC=3C=C4C(=CC3)N=CS4)=NC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)