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Art. -Nr.: HY-19241

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CP-85958

CP-85958 is a specific leukotriene D₄ (LTD₄) receptor antagonist. CP-85958 can be used in the research of inflammatory diseases such as asthma.

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CAS. Nr.: 134002-60-1
Formel: C₂₅H₂₀FNO₅S
Molecular Weight:465.49

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CP-85958 Chemical Structure

CAS. Nr.: 134002-60-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

CP-85958 is a specific leukotriene D₄ (LTD₄) receptor antagonist. CP-85958 can be used in the research of inflammatory diseases such as asthma^[1].

IC₅₀ & Target^[1]

LTD₄

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	8.1 μM Compound: 5 ((+)-CP-85958)	Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells	10.1016/0960-894X(95)00225-I
U-937	IC₅₀	0.31 μM Compound: 3	Compound was evaluated for influx of calcium mobilization in human U937 cells Compound was evaluated for influx of calcium mobilization in human U937 cells	[PMID: 9873435]
U-937	IC₅₀	0.31 μM Compound: 3	Compound was tested for its ability to inhibit calcium influx in human U937 cells Compound was tested for its ability to inhibit calcium influx in human U937 cells	[PMID: 9934474]

Chemical Information

CAS. Nr. 134002-60-1
Molecular Weight 465.49
Formel C₂₅H₂₀FNO₅S
SMILES

O=C(O)C1=CC=CC(C[C@@H]2COC3=CC=C(OCC4=NC5=CC(F)=CC=C5S4)C=C3[C@@H]2O)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Marfat A, et al. The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists. Bioorganic & Medicinal Chemistry Letters, 1995, 5(13): 1377-1382.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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CP-85958

Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CP-85958 Related Classifications

HY-19241 Related Classifications