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Art. -Nr.: HY-121293

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CP-944629

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases.

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CAS. Nr.: 668990-94-1
Formel: C₁₉H₁₅F₃N₄O
Molecular Weight:372.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CP-944629 Chemical Structure

CAS. Nr.: 668990-94-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases^[1].

Alle p38 MAPK Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Monocyte	IC₅₀	8.3 nM Compound: 75	Inhibition of LPS-induced TNFalpha production in human monocytes Inhibition of LPS-induced TNFalpha production in human monocytes	[PMID: 16759861]

Chemical Information

CAS. Nr. 668990-94-1
Molecular Weight 372.34
Formel C₁₉H₁₅F₃N₄O
SMILES

FC1=C(C=C(C(C2=C(OC=N2)C3=CN4C(C=C3)=NN=C4C(C)(C)C)=C1)F)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Shashi Nayana, M. R., et al., (2008). CoMFA and docking studies on triazolopyridine oxazole derivatives as p38 MAP kinase inhibitors. European journal of medicinal chemistry, 43(6), 1261–1269. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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