DC-TEAD3in03
DC-TEAD3in03 is a subtype-selective and covalent TEAD3 inhibitor with an IC50 of 0.16 μM. DC-TEAD3in03 exhibits the inhibitory activity on TEAD1/2/4 reduced by more than 100 times. DC-TEAD3in03 has the IC50 for TEAD3 of 1.15 μM in the GAL4-TEAD reporter gene experiment in cells, and it does not interfere with the β-catenin pathway. DC-TEAD3in03 reduces the growth rate of the zebrafish tail fin. DC-TEAD3in03 can be used to study the proportional growth of appendages in vertebrates.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C17H24N2O2
- Molecular Weight:288.38
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle YAP Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
TEAD3 0.16 μM (IC50) |
Chemical Information
-
Molecular Weight 288.38
-
Formel C17H24N2O2
-
SMILES
O=C(C=C)N1CN(CCCOCC2=CC=CC=C2)CCC1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)