DNDI-6510
DNDI-6510 (Compound (S)-x38) is a non-covalent SARS-CoV-2 MPro inhibitor with a IC50 of 0.04 μM. DNDI-6510 has a potent antiviral activity across SARS-CoV-2 and its variants as well as a weak efficacy to SARS-CoV-1. DNDI-6510 significantly improves drug exposure in metabolically humanized mice model (8HUM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C26H23ClN4O3
- Molecular Weight:474.94
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CYP3A4 |
CYP2C8 |
CYP2C9 |
CYP2C19 |
CYP2D6 |
Chemical Information
-
Molecular Weight 474.94
-
Formel C26H23ClN4O3
-
SMILES
CNC(C1(CC1)N2C[C@@]3(C4=C(C2=O)C=CC(Cl)=C4)CCN(C3=O)C5=C6C=CC=CC6=CN=C5)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)