Echiguanine A
Echiguanine A is a phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.04 μg/mL. Echiguanine A inhibits phosphatidylinositol 4-kinase activity in cell membrane extracts. Echiguanine A is applicable for cancer research.
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- CAS. Nr.: 137319-25-6
- Formel: C10H13N7O2
- Molecular Weight:263.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
0.03 μg/mL
Compound: 1 (echiguanine A)
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Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells
Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells
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10.1016/S0960-894X(97)00122-4 |
Echiguanine A (Compound 1) (20 min) potently inhibits phosphatidylinositol-4-kinase derived from A431 cell membranes, with an IC50 value of 0.04 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 137319-25-6
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Molecular Weight 263.26
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Formel C10H13N7O2
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SMILES
O=C1N=C(NC2=C1C(C(NCCC(N)=N)=O)=CN2)N
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Structure Classification
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Initial Source
Streptomyces sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)