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Art. -Nr.: HY-P990956

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Etakafusp alfa

Name: Etakafusp alfa
Brand: MedChemExpress
SKU: HY-P990956
Price: 700.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: AB-248)

Kundenbewertung

Based on 1 Customer Validation

Etakafusp alfa (AB-248) is a humanized antibody that cis-targets CD8β. Etakafusp alfa selectively stimulates CD8+ T cells to produce and secrete more IL-2, while avoiding non-specific activation of NK cells and Tregs. Etakafusp alfa can be used for immunological research on advanced or metastatic solid tumors.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit : 99.23%
CAS. Nr.: 2852680-28-3

Speicherung:

Shipping with dry ice

Please store the product under the recommended conditions in the Certificate of Analysis.

Etakafusp alfa Chemical Structure

CAS. Nr.: 2852680-28-3

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Clinical Trial
- Conjugated
- Reconstitution
- Format
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

^[1]

CD8β

IL-2

Alle Interleukin Related Isoform-spezifische Produkte anzeigen :

In Vitro

Adaptive ImmunityCytokines & ChemokinesInnate Immunity

Adaptive Immunity

Cytokines & Chemokines

Innate Immunity

Etakafusp alfa (AB248) induces the expected IL-2 gene signature in CD8⁺ T-cells and prevents NK-cell driven, non-specific cytokine secretion in human PBMCs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Conjugated

Unconjugated

Reconstitution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa-PROTEIN

Anwendung

ELISA, FACS, Functional assay

Chemical Information

CAS. Nr. 2852680-28-3
Appearance Liquid
Color Colorless to light yellow
SMILES

[Etakafusp alfa]
Synonyms

AB-248
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Verweise

[1]. Gabizon-Peretz S, et al. Advances in Cancer Immunotherapy for Solid Tumors. Adv Sci (Weinh). 2026 Jun;13(35):e76020.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Clinical Trial
- Conjugated
- Reconstitution
- Format
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise

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Art. -Nr.:
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CAS. Nr.:
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Etakafusp alfa

Alle Interleukin Related Isoform-spezifische Produkte anzeigen