YPEL5 - yippee like 5 Gene

Also Known as CGI-127

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51646

About YPEL5

Cytogenetic location: 2p23.1 Genomic coordinates (GRCh38): 2:30,147,007-30,160,533 (from NCBI)

This gene has 10 transcripts (splice variants), 279 orthologues and 10 paralogues. Ubiquitous expression in bone marrow (RPKM 117.0), testis (RPKM 35.1) and 24 other tissues.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in cell population proliferation. Part of ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

YPEL5 Products (4)

mRNA Protein Name
NM_001127399.2 NP_001120871.1 protein yippee-like 5
NM_001127400.2 NP_001120872.1 protein yippee-like 5
NM_001127401.2 NP_001120873.1 protein yippee-like 5
NM_016061.3 NP_057145.1 protein yippee-like 5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
20580816 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of ubiquitin ligase complex IDA
IDA: Inferred from direct assay
29911972 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YPEL5 Protein Structure

Yippee-Mis18

Yippee-Mis18: Yippee zinc-binding/DNA-binding /Mis18, centromere assembly (14 - 106)

  • 0
  • 100
  • 121 a.a.
Protein Preferred Names Protein Names

protein yippee-like 5

YPEL5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
YPEL5 P62699 GSC2 Homo sapiens O15499
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 GSC2 Homo sapiens O15499
Y2H Array
32296183
Intra
YPEL5 P62699 PLAGL2 Homo sapiens Q9UPG8
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 PLAGL2 Homo sapiens Q9UPG8
Validated Y2H
32296183
Intra
YPEL5 P62699 PLAGL2 Homo sapiens Q9UPG8
Y2H Array
32296183
Intra
YPEL5 P62699 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 PFDN5 Homo sapiens Q99471
Validated Y2H
32296183
Intra
YPEL5 P62699 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
Intra
YPEL5 P62699 PSMA1 Homo sapiens P25786
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 PSMA1 Homo sapiens P25786
Y2H Array
32296183
Intra
YPEL5 P62699 TRAF5 Homo sapiens O00463
Y2H Array
32296183
Intra
YPEL5 P62699 TRAF5 Homo sapiens O00463
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
Intra
YPEL5 P62699 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
YPEL5 P62699 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
YPEL5 P62699 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
YPEL5 P62699 CTDSP1 Homo sapiens Q9GZU7
Y2H Prey Pooling
32296183
Intra
YPEL5 P62699 CTDSP1 Homo sapiens Q9GZU7
Validated Y2H
32296183
Intra
YPEL5 P62699 CTDSP1 Homo sapiens Q9GZU7
Y2H Array
32296183
Intra
YPEL5 P62699 SHC3 Homo sapiens Q92529
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-183077 BRD4 degrader-7 Degrader / Unkown
HY-RS15933 YPEL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21809 Ypel5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28325 Ypel5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus YPEL5 RGD RGD:1309657
Canis familiaris YPEL5 VGNC VGNC:48501
Felis catus YPEL5 VGNC VGNC:67149
Macaca mulatta YPEL5 VGNC VGNC:79128
Bos taurus YPEL5 VGNC VGNC:37037
Mus musculus YPEL5 MGD MGI:1916937
Others YPEL5 NCBI