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Art. -Nr.: HY-W727999

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Koenimbine

Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer.

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CAS. Nr.: 21087-98-9
Formel: C₁₉H₁₉NO₂
Molecular Weight:293.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Koenimbine Chemical Structure

CAS. Nr.: 21087-98-9

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
B16-4A5	IC₅₀	1.2 μM Compound: 13	Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control	[PMID: 23376010]
DU-145	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HCT-116	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HeLa	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HepG2	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
OVCAR-3	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
PA-1	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]

Chemical Information

CAS. Nr. 21087-98-9
Molecular Weight 293.36
Formel C₁₉H₁₉NO₂
SMILES

CC1=CC2=C(NC3=C2C=C(C=C3)OC)C4=C1OC(C)(C=C4)C
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Astaneh M, et al. Assessment of anti-cancer effects of koenimbine on colon cancer cells. Hum Antibodies. 2020;28(3):185-190. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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