Neramexane mesylate
Neramexane mesylate is an α9α10 cholinergic nicotinic receptors and N-methyl-D-aspartate receptors(NMDA) antagonist. Neramexane mesylate can improve moderate to severe tinnitus, and also shows neuroprotective effects.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 457068-92-7
- Formel: C12H27NO3S
- Molecular Weight:265.41
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle iGluR Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS. Nr. 457068-92-7
-
Molecular Weight 265.41
-
Formel C12H27NO3S
-
SMILES
NC1(CC(C)(CC(C)(C1)C)C)C.CS(=O)(O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Suckfüll M, et al. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of neramexane in patients with moderate to severe subjective tinnitus. BMC Ear Nose Throat Disord. 2011;11:1. Published 2011 Jan 11. [Content Brief]
[2]. Sukhotina IA, et al. Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane. Behav Pharmacol. 2004;15(3):207-214. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)