Schizanrin D
Schizanrin D (Schizarin D) is a C18 Dibenzocyclooctadiene lignin. Schizanrin D can be derived from dried stems of Kadsura matsudai. Schizanrin D inhibits HBeAg production. Schizanrin D is inactive in vitro against HIV replication.
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- CAS. Nr.: 343326-65-8
- Formel: C27H32O8
- Molecular Weight:484.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
Schizanrin D (10-20 μg/mL; 3 days) inhibits HBeAg production in MS-G2 cells at 10 μg/mL (20.6 μM) with a 25.8% decrease but is cytotoxic at 20 μg/mL (41.3 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
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Cell Line:MS-G2 cells (HBV DNA-integrated hepatoblastoma-derived cell line)
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Concentration:10 μg/mL (20.6 μM); 20 μg/mL (41.3 μM)
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Incubation Time:3 days
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Result:Inhibited HBeAg production with a 25.8% decrease at 10 μg/mL (20.6 μM); Caused cytotoxicity with an AST value of 47.8 IU/L (indicating cell damage) at 20 μg/mL (41.3 μM).
Chemical Information
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CAS. Nr. 343326-65-8
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Molecular Weight 484.54
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Formel C27H32O8
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SMILES
C/C=C(C)/C(O[C@H]1[C@H](C)[C@H](C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3O)=O
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Synonyms
Schizarin D
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)