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Art. -Nr.: HY-P10809

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VAMP

Kundenbewertung

Based on 1 Customer Validation

VAMP, a tetrapeptide, is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 1.00 μM and a K_d of 6.89 μM. VAMP effectively targets the DPP-IV-GLP-1 axis and can be used for the study of type 2 diabetes.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 98.13%
CAS. Nr.: 3103992-61-3
Formel: C₁₈H₃₂N₄O₅S
Molecular Weight:416.54

Speicherung:

Sealed storage, away from moisture.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

VAMP Chemical Structure

CAS. Nr.: 3103992-61-3

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Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Clinical Trial
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

DPP-4

1 μM (IC₅₀)

DPP-4

6.89 μM (Kd)

Alle Dipeptidyl Peptidase Isoform-spezifische Produkte anzeigen :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS. Nr. 3103992-61-3
Appearance Solid
Molecular Weight 416.54
Formel C₁₈H₃₂N₄O₅S
Color White to off-white
Sequence

Val-Ala-Met-Pro
Sequence Shortening

VAMP
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (240.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4007 mL

12.0036 mL

24.0073 mL

5 mM

0.4801 mL

2.4007 mL

4.8015 mL

10 mM

0.2401 mL

1.2004 mL

2.4007 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Haihong Chen, et al. A novel bifunctional peptide VAMP mined from hemp seed protein hydrolysates improves glucose homeostasis by inhibiting intestinal DPP-IV and increasing the abundance of Akkermansia muciniphila. bioRxiv. July 23, 2024.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4007 mL	12.0036 mL	24.0073 mL	60.0182 mL
	5 mM	0.4801 mL	2.4007 mL	4.8015 mL	12.0036 mL
	10 mM	0.2401 mL	1.2004 mL	2.4007 mL	6.0018 mL
	15 mM	0.1600 mL	0.8002 mL	1.6005 mL	4.0012 mL
	20 mM	0.1200 mL	0.6002 mL	1.2004 mL	3.0009 mL
	25 mM	0.0960 mL	0.4801 mL	0.9603 mL	2.4007 mL
	30 mM	0.0800 mL	0.4001 mL	0.8002 mL	2.0006 mL
	40 mM	0.0600 mL	0.3001 mL	0.6002 mL	1.5005 mL
	50 mM	0.0480 mL	0.2401 mL	0.4801 mL	1.2004 mL
	60 mM	0.0400 mL	0.2001 mL	0.4001 mL	1.0003 mL
	80 mM	0.0300 mL	0.1500 mL	0.3001 mL	0.7502 mL
	100 mM	0.0240 mL	0.1200 mL	0.2401 mL	0.6002 mL

Keywords

100 mg

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Clinical Trial
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

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VAMP

Metabolism/Protease Compound Library

Natural Product Library

Clinical Compound Library

Drug Repurposing Compound Library

Anti-diabetic Compound Library

Peptide Library

Plant-Sourced Natural Product Library

Metabolic Enzyme Compound Library

Protease Inhibitor Library

Highly Selective Inhibitors Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Drug Repurposing Compound Library Plus

Clinical Compound Library Plus

Peptide Compound Library

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

Amino Acid Metabolism Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Mass Spectrometry Natural Product Library

Alle Dipeptidyl Peptidase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

VAMP

Metabolism/Protease Compound Library

Natural Product Library

Clinical Compound Library

Drug Repurposing Compound Library

Anti-diabetic Compound Library

Peptide Library

Plant-Sourced Natural Product Library

Metabolic Enzyme Compound Library

Protease Inhibitor Library

Highly Selective Inhibitors Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Drug Repurposing Compound Library Plus

Clinical Compound Library Plus

Peptide Compound Library

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

Amino Acid Metabolism Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Mass Spectrometry Natural Product Library

Alle Dipeptidyl Peptidase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

VAMP Related Classifications

HY-P10809 Related Classifications