Niruriside
Niruriside is a HIV REV/RRE complex inhibitor. Niruriside specifically inhibits the binding interaction between HIV REV protein and RRE RNA, with an IC50 of 3.3 μM, and shows no significant activity against the unrelated R17 capsid protein/operator RNA binding system. At the tested concentrations, Niruriside fails to protect CEM-SS cells from acute HIV-1 infection. Niruriside can be used in the research of human immunodeficiency virus (HIV) infection.
For research use only. We do not sell to patients.
- CAS No.: 173268-90-1
- Formula: C38H42O17
- Molecular Weight:770.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Niruriside (260 μM; 6 days post-infection, plus 4 h XTT incubation) does not protect CEM-SS cells from acute HIV-1 RF infection at concentrations up to 260 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CEM-SS cells infected with HIV-1 RF
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Concentration:260 μM
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Incubation Time:6 days post-infection, plus 4 h XTT incubation
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Result:Did not protect CEM-SS cells from acute HIV-1 infection at concentrations.
Chemical Information
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CAS No. 173268-90-1
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Molecular Weight 770.73
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Formula C38H42O17
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SMILES
O=C(O[C@@H]1[C@@H](O)[C@H](COC(/C=C/C2=CC=CC=C2)=O)O[C@@]1(O[C@@H]3[C@H](OC(C)=O)[C@@H](O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3)COC(C)=O)/C=C/C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Niruriside Related Classifications
HY-165513 Related Classifications
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