ATX inhibitor 12
ATX inhibitor 12 (compound 20) is an orally active and potent ATX (autotaxin) inhibitor, with an IC50 of 1.72 nM. ATX inhibitor 12 effectively alleviates lung structural damage with fewer fibrotic lesions at an oral dose of 60 mg/kg in C57Bl/6J mice. ATX inhibitor 12 can be uesd for idiopathic pulmonary fibrosis (IPF) research.
For research use only. We do not sell to patients.
- CAS No.: 2771312-16-2
- Formula: C30H34FN5O2
- Molecular Weight:515.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Autotaxin 1.72 nM (IC50) |
Chemical Information
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CAS No. 2771312-16-2
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Molecular Weight 515.62
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Formula C30H34FN5O2
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SMILES
CCC1=C(N2C=C(C=C(C2=N1)C)C3=CC=C(C=C3)CN4CCC(CC4)O)NC(NCC5=CC=C(C=C5)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATX inhibitor 12 Related Classifications
HY-144743 Related Classifications
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