ATX inhibitor 15
ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model.
For research use only. We do not sell to patients.
- CAS No.: 2484811-52-9
- Formula: C27H32ClN5O4S
- Molecular Weight:558.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
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Autotaxin 2.17 nM (IC50) |
Chemical Information
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CAS No. 2484811-52-9
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Molecular Weight 558.09
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Formula C27H32ClN5O4S
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SMILES
O=C(NCC1=CC=C(C(Cl)=C1)OC)NC2=CN(CC)C3=C2C=C(C4=NC(CN(CCO)CCO)=CS4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATX inhibitor 15 Related Classifications
HY-143420 Related Classifications
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