ATX inhibitor 25
ATX inhibitor 25 (Compound 29) is an orally active Autotaxin inhibitor with an IC50 of 1.08 nM. ATX inhibitor 25 exhibits excellent in vitro metabolic stability, with a t1/2 of more than 170 minutes. In the bleomycin (HY-108345)-induced pulmonary fibrosis mouse model, orally administered ATX inhibitor 25 shows anti-fibrotic effects.
For research use only. We do not sell to patients.
- CAS No.: 2951100-44-8
- Formula: C23H20ClFN4O5
- Molecular Weight:486.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2951100-44-8
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Molecular Weight 486.88
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Formula C23H20ClFN4O5
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SMILES
CC1=C(C(NC2=CC(C(O)=O)=C(F)C=C2)=O)C3=CC(OC)=C(Cl)C=C3N1C4=CN(COC)N=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATX inhibitor 25 Related Classifications
HY-168930 Related Classifications
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