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Cat. No.: HY-168505

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MSC-5046

MSC-5046 is a selective TEAD1 inhibitor.

For research use only. We do not sell to patients.

Formula: C₂₄H₁₈F₃N₅O₃
Molecular Weight:481.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MSC-5046 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MSC-5046 is a selective TEAD1 inhibitor^[1].

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Chemical Information

Molecular Weight 481.43
Formula C₂₄H₁₈F₃N₅O₃
SMILES

FC(C=N1)=CN2C1=NC=C2C(NCC3=C(CNC(C=C)=O)C(F)=C(OC4=CC=C(F)C=C4)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Carswell E, et al. Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129981. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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MSC-5046

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Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MSC-5046 Related Classifications

HY-168505 Related Classifications