Thiocarlide
Based on 1 Customer Validation
Thiocarlide is a potent antibacterial agent. Thiocarlide inhibits Mycobacterium tuberculosis H37Rv, Mycobacterium bovisBCG, Mycobacterium avium, and Mycobacterium aurum A+ with MICs of 2.5, 0.5, 2.0 and 2.0 μg/mL, respectively.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 910-86-1
- Formula: C23H32N2O2S
- Molecular Weight:400.58
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 910-86-1
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Appearance Solid
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Molecular Weight 400.58
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Formula C23H32N2O2S
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Color White to off-white
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SMILES
S=C(NC1=CC=C(OCCC(C)C)C=C1)NC2=CC=C(OCCC(C)C)C=C2
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Synonyms
Isoxyl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 30 mg/mL (74.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (263 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4964 mL | 12.4819 mL | 24.9638 mL | 62.4095 mL |
| 5 mM | 0.4993 mL | 2.4964 mL | 4.9928 mL | 12.4819 mL | |
| 10 mM | 0.2496 mL | 1.2482 mL | 2.4964 mL | 6.2410 mL | |
| 15 mM | 0.1664 mL | 0.8321 mL | 1.6643 mL | 4.1606 mL | |
| 20 mM | 0.1248 mL | 0.6241 mL | 1.2482 mL | 3.1205 mL | |
| 25 mM | 0.0999 mL | 0.4993 mL | 0.9986 mL | 2.4964 mL | |
| 30 mM | 0.0832 mL | 0.4161 mL | 0.8321 mL | 2.0803 mL | |
| 40 mM | 0.0624 mL | 0.3120 mL | 0.6241 mL | 1.5602 mL | |
| 50 mM | 0.0499 mL | 0.2496 mL | 0.4993 mL | 1.2482 mL | |
| 60 mM | 0.0416 mL | 0.2080 mL | 0.4161 mL | 1.0402 mL |
Thiocarlide Related Classifications
HY-113784 Related Classifications
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