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Art. -Nr.: HY-N20727

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Austocystins I

Austocystins I is a toxin and protein tyrosine phosphatase inhibitor, with an IC₅₀ of 16 μM against MEG2 and an IC₅₀ of 19 μM against CDC25B. Austocystins I exhibits lethal toxicity to brine shrimp. Austocystins I can be used in the research of cancer and type 2 diabetes.

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CAS. Nr.: 58775-51-2
Formel: C₁₈H₁₂O₇
Molecular Weight:340.28

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Austocystins I Chemical Structure

CAS. Nr.: 58775-51-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Austocystins I (0.096-200 μg/mL; 24 h) exhibits lethal toxicity towards brine shrimp nauplii with an LC₅₀ of 2.9 μM^[1].
Austocystins I (48 h) does not exhibit significant cytotoxicity towards Vero cells, with a TC₅₀ > 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Metabolic Diseases

Chemical Information

CAS. Nr. 58775-51-2
Molecular Weight 340.28
Formel C₁₈H₁₂O₇
SMILES

O[C@]12C3=C(C4=C(OC5=CC=CC(O)=C5C4=O)C=C3O[C@@]1([H])OC=C2)OC
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganism
Aspergillus puniceus SCSIO z021
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Liang X, et al. Mycotoxins as inhibitors of protein tyrosine phosphatases from the deep-sea-derived fungus Aspergillus puniceus SCSIO z021. Bioorganic chemistry. 2021 Feb;107:104571. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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