1. Autophagy
  2. Autophagy
  3. Autogramin-1

Autogramin-1 

Cat. No.: HY-128339 Purity: >98.0%
Handling Instructions

Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM).

For research use only. We do not sell to patients.

Autogramin-1 Chemical Structure

Autogramin-1 Chemical Structure

CAS No. : 2375541-73-2

Size Price Stock Quantity
5 mg USD 710 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1200 Get quote
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Based on 1 publication(s) in Google Scholar

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Description

Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM)[1].

Molecular Weight

485.56

Formula

C₂₃H₂₇N₅O₅S

CAS No.

2375541-73-2

SMILES

O=C(N1)N(CCC)C(C2=C1C=C(C(NC3=NC(CCN(C(OC(C)(C)C)=O)C4)=C4S3)=O)C=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.94 mg/mL (14.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0595 mL 10.2974 mL 20.5948 mL
5 mM 0.4119 mL 2.0595 mL 4.1190 mL
10 mM 0.2059 mL 1.0297 mL 2.0595 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: >98.0%

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Keywords:

Autogramin-1Autogramin1Autogramin 1AutophagyInhibitorinhibitorinhibit

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Autogramin-1
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