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Cat. No.: HY-183558

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AV-DL055

AV-DL055 is a conjugate of the toxin molecule Exatecan (HY-13631) and the linker AV-L03 (HY-183678). AV-DL055 can be used to construct ADCs, such as T-DL055.

For research use only. We do not sell to patients.

CAS No.: 3107874-31-4
Formula: C₅₉H₆₃FN₈O₂₅
Molecular Weight:1303.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AV-DL055 Chemical Structure

CAS No.: 3107874-31-4

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Use of MCE Products

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Biological Activity

Description

AV-DL055 is a conjugate of the toxin molecule Exatecan (HY-13631) and the linker AV-L03 (HY-183678). AV-DL055 can be used to construct ADCs, such as T-DL055^[1].

All Drug-Linker Conjugates for ADC Isoforms :

All Topoisomerase Isoforms :

Chemical Information

CAS No. 3107874-31-4
Molecular Weight 1303.17
Formula C₅₉H₆₃FN₈O₂₅
SMILES

O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C(COC(N[C@H]3CCC4=C5C3=C(CN6C(C(COC([C@@]7(CC)O)=O)=C7C=C68)=O)C8=NC5=CC(F)=C4C)=O)C=C2NC(CCNC([C@@H](NC(CN9C(C=CC9=O)=O)=O)CCCC(N[C@H]%10[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O%10)=O)=O)=O)O1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jammalamadaka V, et al. Exatecan Payload-Based Antibody-Drug Conjugates with a Short Hydrophilic Cleavable Linker. ACS Med Chem Lett. 2026;17(5):1035-1042. Published 2026 Apr 23. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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AV-DL055

All Drug-Linker Conjugates for ADC Isoforms

All Topoisomerase Isoforms