Azepexole hydrochloride
Based on 1 Customer Validation
Azepexole hydrochloride (B-HT 933 dihydrochloride; Oxazoloazepin dihydrochloride) is a selective agonist for α 2-adrenoceptor, with pKi of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions with IC50 of 78.72 nM. Azepexole hydrochloride exhibits antitussive and analgesic efficacy.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 147663-20-5
- Formula: C9H16ClN3O
- Molecular Weight:217.70
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Adrenergic Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 147663-20-5
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Appearance Oil
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Molecular Weight 217.70
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Formula C9H16ClN3O
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Color Brown to orange
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SMILES
CCN(CC1)CCC2=C1OC(N)=N2.Cl
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Synonyms
B-HT 933 hydrochloride; Oxazoloazepin hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Altamirano-Espinoza AH, et al. Specific role of α2A - and α2B -, but not α2C -, adrenoceptor subtypes in the inhibition of the vasopressor sympathetic out-flow in diabetic pithed rats. Basic Clin Pharmacol Toxicol. 2015;117(1):31-38. [Content Brief]
[2]. Capey S. Azepexole[J]. 2007.Pharm: The Comprehensive Pharmacology Reference.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)