BAY-588
Based on 1 Customer Validation
BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.99%
- CAS 番号: 1799759-24-2
- 分子式: C27H25F4N5O2
- 分子量:527.51
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
IC50 & Target
IC50=1.18μM(GLUT1)[1], IC50>10μM(GLUT2)[1], IC50=5.47μM(GLUT3)[1], IC50=0.5μM(GLUT4)[1]
化学情報
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CAS 番号 1799759-24-2
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性状 Solid
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分子量 527.51
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分子式 C27H25F4N5O2
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Color White to off-white
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SMILES
O=C(N)C1=NC2=CC(F)=CC=C2C(C(NC3=C(N(N=C3C(F)(F)F)CC4=CC=C(C=C4)C(C)(C)C)C)=O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (189.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8957 mL | 9.4785 mL | 18.9570 mL | 47.3925 mL |
| 5 mM | 0.3791 mL | 1.8957 mL | 3.7914 mL | 9.4785 mL | |
| 10 mM | 0.1896 mL | 0.9478 mL | 1.8957 mL | 4.7392 mL | |
| 15 mM | 0.1264 mL | 0.6319 mL | 1.2638 mL | 3.1595 mL | |
| 20 mM | 0.0948 mL | 0.4739 mL | 0.9478 mL | 2.3696 mL | |
| 25 mM | 0.0758 mL | 0.3791 mL | 0.7583 mL | 1.8957 mL | |
| 30 mM | 0.0632 mL | 0.3159 mL | 0.6319 mL | 1.5797 mL | |
| 40 mM | 0.0474 mL | 0.2370 mL | 0.4739 mL | 1.1848 mL | |
| 50 mM | 0.0379 mL | 0.1896 mL | 0.3791 mL | 0.9478 mL | |
| 60 mM | 0.0316 mL | 0.1580 mL | 0.3159 mL | 0.7899 mL | |
| 80 mM | 0.0237 mL | 0.1185 mL | 0.2370 mL | 0.5924 mL | |
| 100 mM | 0.0190 mL | 0.0948 mL | 0.1896 mL | 0.4739 mL |