2. MAPK/ERK Pathway Stem Cell/Wnt
  3. ERK
  4. BAY-693

BAY-693 is a highly potent and highly selective ERK5 inhibitor with an IC50 of 6.40 μM. BAY-693 reduces the transcriptional activity of MEF2. BAY-693 is applicable for cancer research.

For research use only. We do not sell to patients.

BAY-693

BAY-693 Chemical Structure

CAS No. : 2306302-48-5

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BAY-693 Related Antibodies

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Description

BAY-693 is a highly potent and highly selective ERK5 inhibitor with an IC50 of 6.40 μM. BAY-693 reduces the transcriptional activity of MEF2. BAY-693 is applicable for cancer research[1].

IC50 & Target[1]

ERK5

6.4 μM (IC50)

In Vitro

BAY-693 (Compound 42) (16 h) inhibits ERK5-mediated MEF2 transcriptional activity in EGF-stimulated SN12C-MEF2-luc kidney cancer cells with an IC50 of 11.0 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BAY-693 Related Antibodies
Molecular Weight

529.56

Formula

C26H30F3N7O2
CAS No.
SMILES

O=C(N1CCC(CC1)C2=NC(C)=NC3=CC(N4CCN(CC4)C)=CN=C32)C5=CC=C(C=C5N)OC(F)(F)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BAY-693 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-6932306302-48-5BAY693BAY 693ERKExtracellular signal regulated kinasesEGFERK5humanSN12C-MEF2-luc kidney cancer cellsMEF2Inhibitorinhibitorinhibit

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