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Cat. No.: HY-W1058380

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BChE-IN-53

BChE-IN-53 is a butyrylcholinesterase (BChE) inhibitor with an IC₅₀ value of 119.0 μM and is inactive against α-glucosidase. BChE-IN-53 can be used for the research of alzheimer's disease, type 2 diabetes mellitus.

For research use only. We do not sell to patients.

CAS No.: 25870-73-9
Formula: C₁₆H₁₅NO₂
Molecular Weight:253.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BChE-IN-53 Chemical Structure

CAS No.: 25870-73-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target^[1]

BChE

119 μM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

In Vitro

BChE-IN-53 (5-500 μM; 15 min enzyme incubation, 10 min substrate reaction) inhibits purified butyrylcholinesterase enzyme with an IC₅₀ of 119.0 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 25870-73-9
Molecular Weight 253.30
Formula C₁₆H₁₅NO₂
SMILES

O=C(C=CC1=CC=C(OC)C=C1)C2=CC=C(N)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jabeen F, et al. Dual inhibition of the α-glucosidase and butyrylcholinesterase studied by molecular field topology analysis. European journal of medicinal chemistry. 2014 Jun 10;80:228-42. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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BChE-IN-53

All Cholinesterase (ChE) Isoforms