Belvarafenib (Standard)
Belvarafenib (Standard) is the analytical standard of Belvarafenib (HY-109080). This product is intended for research and analytical applications. Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.
For research use only. We do not sell to patients.
- CAS No.: 1446113-23-0
- Formula: C23H16ClFN6OS
- Molecular Weight:478.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1446113-23-0
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Molecular Weight 478.93
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Formula C23H16ClFN6OS
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SMILES
O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C
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Synonyms
HM95573 (Standard); GDC-5573 (Standard); RG6185 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. WO 2013/100632 A1.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)