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Bfl-1-IN-3

Bfl-1-IN-3 (Compound 56) is a selective, competitive inhibitor for Bfl-1 on BID binding site with Ki of 105 nM. Bfl-1-IN-3 inhibits the proliferation of cell pfeiffer and MV4-11, with IC50 of 6.92 μM and 12.6 μM. Bfl-1-IN-3 induces apoptosis in pfeiffer cells. Bfl-1-IN-3 overcomes Venetoclax (HY-15531) resistance at the cellular level, and shows synergistically enhanced anti-tumor activity with Venetoclax.

For research use only. We do not sell to patients.

  • Formula: C40H38ClN5O4
  • Molecular Weight:688.21
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Bfl-1-IN-3 Chemical Structure
    Bfl-1-IN-3 Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All Bcl-2 Family Isoforms

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  • Bfl-1-IN-3