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Cat. No.: HY-18861

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BIRB-1017

BIRB-1017 is a potent inhibitor of p38 MAP kinase. BIRB-1017 can be used in inflammation research.

For research use only. We do not sell to patients.

CAS No.: 294848-51-4
Formula: C₃₅H₃₉N₆O₂
Molecular Weight:575.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BIRB-1017 Chemical Structure

CAS No.: 294848-51-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BIRB-1017 is a potent inhibitor of p38 MAP kinase. BIRB-1017 can be used in inflammation research^[1].

IC₅₀ & Target^[1]

p38 MAP kinase

All p38 MAPK Isoforms :

Chemical Information

CAS No. 294848-51-4
Molecular Weight 575.72
Formula C₃₅H₃₉N₆O₂
SMILES

CC1=CC=C([N]2=C(NC(NC3=CC=C(C4=CC=C(CN5CCOCC5)N=C4)C6=C3C=CC=C6)=O)CC(C(C)(C)C)=N2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lu BZ, et al. Development of a Practical Synthesis of 4-[6-(Morpholinomethyl)-pyridin-3-yl] naphthalen-1-amine, a Key Intermediate for the Synthesis of BIRB 1017, a Potent p38 MAP Kinase Inhibitor. Synlett. 2013 Feb;24(03):317-22.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BIRB-1017

All p38 MAPK Isoforms