Bispyribac

Cat. No.: HY-B0869: Data Sheet
SDS
Handling Instructions
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Bispyribac is an acetolactate synthase inhibitor that can be used as a systemic post-emergence herbicide for control of weeds in agriculture. Bispyribac blocks the amino acid synthesis. Bispyribac has low acute toxicity in animal models.

For research use only. We do not sell to patients.

Bispyribac Chemical Structure

CAS No. : 125401-75-4

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
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Other Forms of Bispyribac:

Bispyribac sodium In-stock

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Description

In Vivo

Bispyribac (p.o.; single dose) exhibits an acute oral LD₅₀ of 4111 mg/kg in male rats and 2635 mg/kg in female rats, and exhibits an acute oral LD₅₀ of 3524 mg/kg in male and female mice, indicating low acute oral toxicity^[1].
Bispyribac (enteral; single dose) reaches peak plasma concentrations 1-2 hours after enteral administration in Rattus norvegicus, has an apparent elimination half-life of 5-7 hours, and is primarily eliminated unchanged in feces via biliary excretion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Rats^[1]
Dosage:	4111 mg/kg (male rats); 2635 mg/kg (female rats)
Administration:	p.o.; single dose
Result:	Determined an acute oral LD₅₀ of 4111 mg/kg in male rats. Determined an acute oral LD₅₀ of 2635 mg/kg in female rats.

Animal Model:	Mice^[1]
Dosage:	3524 mg/kg
Administration:	p.o.; single dose
Result:	Determined an acute oral LD₅₀ of 3524 mg/kg in male and female mice.

Molecular Weight

430.37

Formula

C₁₉H₁₈N₄O₈

CAS No.

125401-75-4

Appearance

Solid

SMILES

O=C(C1=C(OC2=NC(OC)=CC(OC)=N2)C=CC=C1OC3=NC(OC)=CC(OC)=N3)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

Purity & Documentation

Data Sheet (270 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. Bandara Gawarammana I, et al. Acute human self-poisoning with bispyribac-containing herbicide Nominee: a prospective observational study. Clin Toxicol (Phila). 2010;48(3):198-202. [Content Brief]

Bispyribac Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bispyribac125401-75-4Acetolactate Synthase (ALS)HerbicideAcetohydroxyacid synthasebacterialeucinevalineanimal modelsplantsfungiisoleucineratsacetolactate synthasemiceInhibitorinhibitorinhibit

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