BLX-3887
Based on 1 Customer Validation
BLX-3887 is a selective 15-lipoxygenase type 1 (15-LO-1) inhibitor with an IC50 of 32 nM. BLX-3887 can be utilized in research related to the 15-LO pathways.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 934758-70-0
- Formula: C10H5Cl3FN3O
- Molecular Weight:308.52
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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15-LOX-1 32 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
32 nM
Compound: 3c
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Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic acid substrate addition by HPLC-UV spectroscopy
Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic acid substrate addition by HPLC-UV spectroscopy
|
[PMID: 26037322] |
Chemical Information
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CAS No. 934758-70-0
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Appearance Solid
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Molecular Weight 308.52
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Formula C10H5Cl3FN3O
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Color White to off-white
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SMILES
O=C(C1=NNC(Cl)=C1Cl)NC2=CC=C(F)C=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)