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Cat. No.: HY-173159

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BMS-185354

BMS-185354 is a selective RARγ activator with an EC₅₀ value of 28 nM. BMS-185354 is promising for research of cancers.

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CAS No.: 110952-22-2
화학식: C₂₆H₂₇NO₃
분자량:401.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BMS-185354 Chemical Structure

CAS No.: 110952-22-2

사이즈

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수량

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

BMS-185354 is a selective RARγ activator with an EC₅₀ value of 28 nM. BMS-185354 is promising for research of cancers^[1].

IC₅₀ & Target

RXRγ

28 nM (EC₅₀)

All RAR/RXR Isoforms :

Chemical Information

CAS No. 110952-22-2
분자량 401.50
화학식 C₂₆H₂₇NO₃
SMILES

O=C(C1=CC2=CC=C(/C(C3=CC=C4C(C(C)(CCC4(C)C)C)=C3)=N/O)C=C2C=C1)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ostrowski J, et al. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J Biol Chem. 1998 Feb 6;273(6):3490-5. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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BMS-185354

All RAR/RXR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BMS-185354 Related Classifications

HY-173159 Related Classifications