BMS-978299
BMS-978299 is an IRAK4 inhibitor that can be used for the study of immune disorders.
For research use only. We do not sell to patients.
- CAS No.: 1610016-88-0
- Formula: C21H24FN5O2S
- Molecular Weight:429.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Price
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Quantity
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target[1]
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IRAK4 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
230 nM
Compound: 12
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Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
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[PMID: 32676146] |
Chemical Information
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CAS No. 1610016-88-0
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Molecular Weight 429.51
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Formula C21H24FN5O2S
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SMILES
C(NC[C@H](C(C)(C)O)F)(=O)C=1C(NC2CC2)=CC(NC=3C=C4C(=CC3)N=CS4)=NC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
References
Calculators
Molarity Calculator
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Dilution Calculator
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