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Cat. No.: HY-187012

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BRAF ligand-2

BRAF ligand-2 is a BRAF ligand that can be used to synthesize PROTACs, such as Tagarafdeg (HY-153341).

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CAS No.: 2882167-76-0
Formule: C₂₆H₂₉FN₆O₅S
Masse moléculaire:556.61

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BRAF ligand-2 Chemical Structure

CAS No.: 2882167-76-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

BRAF ligand-2 is a BRAF ligand that can be used to synthesize PROTACs, such as Tagarafdeg (HY-153341)^[1].

IC₅₀ & Target^[1]

Braf

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Chemical Information

CAS No. 2882167-76-0
Masse moléculaire 556.61
Formule C₂₆H₂₉FN₆O₅S
SMILES

O=C(C1=C2)N(C=NC1=CC=C2OC(C(F)=CC=C3N[S](N(C)CC)(=O)=O)=C3C#N)[C@@H]4CC5(OC4)CCNCC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Sowa M E, et al. Preclinical evaluation of CFT1946 as a selective degrader of mutant BRAF for the treatment of BRAF driven cancers[J]. Cancer Research, 2022, 82(12_Supplement): 2158-2158.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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BRAF ligand-2

Voir tous les produits spécifiques à Isoform Raf

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BRAF ligand-2 Related Classifications

HY-187012 Related Classifications