IV-275
IV-275 is an inhibitor of both BRG1 and BRM bromodomains. IV-275 increases the extent of DNA damage induced by Temozolomide (HY-17364) and Bleomycin (HY-108345). IV-275 inhibits the invasiveness of GBM cells. IV-275 enhances Temozolomide-induced cell death and the apoptosis-inducing activity of Temozolomide.
For research use only. We do not sell to patients.
- Formula: C19H18F2N2O3
- Molecular Weight:360.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All SWI/SNF Complex Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 360.35
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Formula C19H18F2N2O3
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SMILES
COC1=CC=C(N2[C@H]3CN([C@@H](C2)C3)C(OC4=CC(F)=C(C=C4)F)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)