LC3in-C42
LC3in-C42 is a cell-active LC3A/B and autophagy covalent inhibitor. LC3in-C42 selectively inhibits the binding of P62 to LC3A/B in vitro and at the cellular level like D5 and can function on a lower concentration.
For research use only. We do not sell to patients.
- Formula: C19H21Cl2N3O2
- Molecular Weight:394.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
LC3in-C42 is discovered utilizing the hybridization of advantageous fragments, whose potency (IC50 = 7.6 nM) has been greatly improved compared with that of DC-LC3inD5[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 394.29
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Formula C19H21Cl2N3O2
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SMILES
O=C1/C(C(CC(C1)C2=C(C(Cl)=CC3=C2C=CN3)Cl)=O)=C/NCCN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)