CD34
CD34 is a heavily glycosylated transmembrane sialomucin expressed on hematopoietic stem and progenitor cells, vascular endothelial cells and fibroblast-like stromal cells. Although its precise ligand interactions remain incompletely defined, CD34 is thought to modulate adhesion, progenitor proliferation and cell migration through negatively charged extracellular mucin domains. The antigen's restricted pattern makes it the clinical standard for enumerating and isolating stem cells for transplantation, and CD34-based immunoselection supplies grafts for autologous and allogeneic use. In diagnostic pathology, CD34 staining labels endothelial cells and is used to identify vascular tumors and stromal lesions such as solitary fibrous tumor.
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CD34 Recombinant Proteins (7)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
