UK 357903
UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC50s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction.
For research use only. We do not sell to patients.
- CAS No.: 247580-98-9
- Formula: C27H34N8O5S
- Molecular Weight:582.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDE5 1.7 nM (IC50) |
PDE6 714 nM (IC50) |
Chemical Information
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CAS No. 247580-98-9
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Molecular Weight 582.67
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Formula C27H34N8O5S
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SMILES
O=C1N=C(C2=C(OCCOC)N=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UK 357903 Related Classifications
HY-19420 Related Classifications
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