019854-B06
019854-B06 is a potent inhibitor of Tat-mediated HIV-1 transcription (IC50 = 1.44 μM), exhibiting antiviral activity against HIV-1 (EC50 = 0.83 μM). 019854-B06 binds to Tat peptide (KD = 33.5 μM), but not to TAR RNA. 019854-B06 neither promotes Tat degradation nor disrupts the Tat/CycT1 complex, supporting a Tat-centric, nondegradative mechanism.
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- Formule: C28H38O5
- Masse moléculaire:454.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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Masse moléculaire 454.60
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Formule C28H38O5
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SMILES
CCCCCCCCCCOC1=CC=C(C=C1)OCC2=C(C=CC=C2)/C(C(OC)=O)=C\OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)