9-Nitrooleate
Based on 1 Customer Validation
9-Nitrooleate, a nitro fatty acid, is a nitro derivative of Oleic acid (HY-N1446). 9-Nitrooleate has potential for use in vascular disease research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.79%
- CAS No.: 875685-44-2
- Formule: C18H33NO4
- Masse moléculaire:327.46
-
Stockage:
Solution, -20°C, 2 years
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
1 μM
Compound: 42
|
Agonist activity at human TRPA1 channel in HEK293 cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imaging
Agonist activity at human TRPA1 channel in HEK293 cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imaging
|
[PMID: 20356305] |
9-Nitrooleate is formed by the reaction of NO with unsaturated fatty acids under oxidative stress conditions. 9-Nitrooleate belongs to a type of nitro-fatty acid. Nitro-fatty acids can exert anti-inflammatory and vascular protective effects by activating the PPARγ pathway or non-PPAR pathways. Especially in cardiovascular disease models, they can antagonize angiotensin II receptors and alleviate hypertension[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 875685-44-2
-
Appearance Liquid
-
Masse moléculaire 327.46
-
Formule C18H33NO4
-
Color Colorless to light yellow
-
SMILES
CCCCCCCC/C=C(CCCCCCCC(O)=O)/[N+]([O-])=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Solution, -20°C, 2 years
Pureté et documentation
-
Fiche technique (263 KB)
-
SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
-
Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)