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Aducanumab

(Synonyms: BIIB037)
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Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows blood-brain-barrier penetration, and can be used for Alzheimer's disease (AD) research.

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  • Pureté: 99.25%
  • CAS No.: 1384260-65-4
  • Masse moléculaire:146.2 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Aducanumab
  • Experimental Validation Results for Aducanumab
  • Experimental Validation Results for Aducanumab
  • Aducanumab Chemical Structure
    Aducanumab Chemical Structure
CAS No.: 1384260-65-4
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Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Aducanumab. The EC50 for this effect is 603.66 ng/mL.

  • 1/16

    The EC50 for this effect is 603.66 ng/mL. Flow cytometric analysis of 1.5×106 HUVEC cells with Aducanumab (HY-P9967, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Aducanumab Chemical Structure
    1/16
  • Aducanumab
  • Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Aducanumab. The EC50 for this effect is 603.66 ng/mL.
  • The EC50 for this effect is 603.66 ng/mL. Flow cytometric analysis of 1.5×106 HUVEC cells with Aducanumab (HY-P9967, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.