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Cat. No.: HY-181584

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AKI-062a

AKI-062a is a non-selective kinase inhibitor, such as a CK1γ inhibitor. AKI-062a binds to and inhibits WNT pathway kinases and GSK3β. At a concentration of 1 μM, AKI-062a binds to 17 kinases, with a binding activity of <10% of that of the control group.

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CAS No.: 1093303-07-1
Formule: C₂₀H₂₁N₇O
Masse moléculaire:375.43

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

AKI-062a Chemical Structure

CAS No.: 1093303-07-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

IC₅₀ & Target

GSK-3β

Voir tous les produits spécifiques à Isoform GSK-3 :

In Vitro

AKI-062a (1 μM) demonstrates non-selective kinase binding, interacting with 17 kinases including the WNT pathway kinase GSK3β^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1093303-07-1
Masse moléculaire 375.43
Formule C₂₀H₂₁N₇O
SMILES

CN(C)CC(NC1=NNC(C1=C2)=CC=C2C(N=N3)=CN3CC4=CC=CC=C4)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Capener JL, et al. Development of a Chemical Probe to Enable Characterization of the Casein Kinase 1γ Subfamily. J Med Chem. 2026 Feb 12;69(3):2666-2684. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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AKI-062a

Voir tous les produits spécifiques à Isoform GSK-3

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

AKI-062a Related Classifications

HY-181584 Related Classifications