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AKIR001

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Based on 1 Customer Validation

AKIR001 is a high-affinity human IgG1 antibody targeting CD44v6. AKIR001 carries LALA-silencing mutations in its FcγR-binding domain to reduce FcγR and C1q interactions, minimizing tissue interactions and limiting CDC and ADCC risks. [177Lu] radiolabeled AKIR001, namely [177Lu]Lu-AKIR001, has anticancer activity against epidermoid carcinoma.

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  • Pureté: 99.41%
  • Masse moléculaire:145.48 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for AKIR001
  • Experimental Validation Results for AKIR001
  • AKIR001 Chemical Structure
    AKIR001 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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AKIR001 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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    Immobilized Human CD44v6 Protein can bind AKIR001. The ED50 for this effect is 86.8 ng/mL.

  • AKIR001 Chemical Structure
    1/16
  • AKIR001
  • Immobilized Human CD44v6 Protein can bind AKIR001. The ED50 for this effect is 86.8 ng/mL.
  • Product Image