ALR-27
ALR-27 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene (LT) production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes.
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- CAS No.: 903639-13-4
- Formule: C19H22O3
- Masse moléculaire:298.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
FLAP[1]
Chemical Information
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CAS No. 903639-13-4
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Masse moléculaire 298.38
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Formule C19H22O3
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SMILES
OC1=CC=C(C=C1)CCC2CCC(CO2)C3=CC=C(C=C3)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALR-27 Related Classifications
HY-155408 Related Classifications
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