ARN23765
ARN23765 is a corrector for F508del-CFTR with an EC50 of 38 pM in human bronchial epithelial cells. ARN23765 improves the maturation and function of F508del-CFTR on the cell membrane, affects the ions transport and secretion, and corrects the pathological mechanism of cystic fibrosis (CF).
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- CAS No.: 2244458-40-8
- Formule: C30H22F5N3O6
- Masse moléculaire:615.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 2244458-40-8
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Masse moléculaire 615.50
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Formule C30H22F5N3O6
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SMILES
OC(C1=CC=C(C=C1)O[C@H]2CCCC3=C2N(N=C3C(F)(F)F)C4=CC(C(N(C)C5=CC6=C(OC(F)(F)O6)C=C5)=O)=CC=C4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ARN23765 Related Classifications
HY-133569 Related Classifications
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