ASIC-IN-1
ASIC-IN-1 is a potent acid sensing ion channel inhibitor with an IC50 value of < 10 µM. ASIC-IN-1 causes a dose- dependent reduction of the pain intensity.
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- CAS No.: 308088-10-0
- Formule: C23H25N3O2
- Masse moléculaire:375.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Activité biologique
Description
IC50 & Target
IC50: < 10 µM (acid sensing ion channel)[1]
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:150-180 g male Sprague-Dawley rats[1]
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Dosage:50 mg/kg
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Administration:I.p.
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Result:Blocked acute tonic pain induced by formalin injection in the paw.
Chemical Information
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CAS No. 308088-10-0
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Masse moléculaire 375.46
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Formule C23H25N3O2
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SMILES
CC1=NC2=CC=CC=C2C(N3CCN(CC(C4=CC=C(OC)C=C4)=O)CC3)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ASIC-IN-1 Related Classifications
HY-147391 Related Classifications
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