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Cat. No.: HY-N16402

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Aspergillusidone D

Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC₅₀ of 0.8  μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research.

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CAS No.: 1454585-77-3
Formule: C₁₉H₁₆Br₂O₅
Masse moléculaire:484.14

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Aspergillusidone D Chemical Structure

CAS No.: 1454585-77-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

Aromatase

0.8 μM (IC₅₀)

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Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	23.72 μM Compound: 1	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay	[PMID: 24016057]

Chemical Information

CAS No. 1454585-77-3
Masse moléculaire 484.14
Formule C₁₉H₁₆Br₂O₅
SMILES

C/C=C(C1=C2C(OC(C3=C(C)C(Br)=C(O)C=C3O2)=O)=C(C(O)=C1Br)C)\C
Structure Classification
- Others
Initial Source
- Microorganisms
Aspergillus unguis
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3(6): 1781-1788.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Aspergillusidone D

Voir tous les produits spécifiques à Isoform Cytochrome P450

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Aspergillusidone D Related Classifications

HY-N16402 Related Classifications